_______________The Other 90% of Science_______________

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20081809

Ong CW et al

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Mod Pathol 2010 Mar;23(3):450-7      
CD133 expression predicts for non-response to chemotherapy in colorectal cancer.


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Clarke R et al

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N Engl J Med 1991 Apr 25;324(17):1149-55      
Hyperhomocysteinemia: an independent risk factor for vascular disease.


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Halaban R et al

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Pigment Cell Melanoma Res 2010 Apr;23(2):190-200      
PLX4032, a selective BRAF(V600E) kinase inhibitor, activates the ERK pathway and enhances cell migration and proliferation of BRAF melanoma cells.


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Spadoni A and Daraio C

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Proc Natl Acad Sci U S A 2010 Apr 20;107(16):7230-4      
Generation and control of sound bullets with a nonlinear acoustic lens.


2059685

Forman D et al

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BMJ 1991 Jun 1;302(6788):1302-5      
Association between infection with Helicobacter pylori and risk of gastric cancer: evidence from a prospective investigation.


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Di LJ et al

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Nat Struct Mol Biol 2010 Nov 21;      
Transcriptional regulation of BRCA1 expression by a metabolic switch.


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Tan WL et al

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Low cytosine triphosphate synthase 2 expression renders resistance to 5-fluorouracil in colorectal cancer.


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Huryn DM et al

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Proc Natl Acad Sci U S A 2011 Apr 26;108(17):6757-62      
Chemical methodology as a source of small-molecule checkpoint inhibitors and heat shock protein 70 (Hsp70) modulators.


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Vignoli M et al

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Thymidylate synthase expression and genotype have no major impact on the clinical outcome of colorectal cancer patients treated with 5-fluorouracil.


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Thomas JO and Kornberg RD

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Proc Natl Acad Sci U S A 1975 Jul;72(7):2626-30      
An octamer of histones in chromatin and free in solution.


2968522

Whyte P et al

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Nature 1988 Jul 14;334(6178):124-9      
Association between an oncogene and an anti-oncogene: the adenovirus E1A proteins bind to the retinoblastoma gene product.


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Mansour SL et al

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Nature 1988 Nov 24;336(6197):348-52      
Disruption of the proto-oncogene int-2 in mouse embryo-derived stem cells: a general strategy for targeting mutations to non-selectable genes.


4153799

Glucksberg H et al

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Transplantation 1974 Oct;18(4):295-304      
Clinical manifestations of graft-versus-host disease in human recipients of marrow from HL-A-matched sibling donors.


6308472

Land H et al

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Nature 1983 Aug 18-24;304(5927):596-6      
Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes.


6329717

Walker JE et al

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EMBO J 1982;1(8):945-51      
Distantly related sequences in the alpha- and beta-subunits of ATP synthase, myosin, kinases and other ATP-requiring enzymes and a common nucleotide binding fold.


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MacMahon B et al

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N Engl J Med 1981 Mar 12;304(11):630-3      
Coffee and cancer of the pancreas.


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Kharitonov SA et al

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Lancet 1994 Jan 15;343(8890):133-5      
Increased nitric oxide in exhaled air of asthmatic patients.


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el-Deiry WS et al

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Cancer Res 1994 Mar 1;54(5):1169-74      
WAF1/CIP1 is induced in p53-mediated G1 arrest and apoptosis.


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Simmons WA et al

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Immunogenetics 1993;38(5):351-8      
Sharing of an HLA-B27-restricted H-Y antigen between rat and mouse.


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Lisitsyn N et al

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Science 1993 Feb 12;259(5097):946-51      
Cloning the differences between two complex genomes.


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Peters WP et al

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J Clin Oncol 1993 Jun;11(6):1132-43      
High-dose chemotherapy and autologous bone marrow support as consolidation after standard-dose adjuvant therapy for high-risk primary breast cancer.


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Kikuchi A et al

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N Engl J Med 1997 Jan 23;336(4):296-7      
Absence of human T-cell lymphotropic virus type I in cutaneous T-cell lymphoma.


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Shao RG et al

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Cancer Res 1997 Sep 15;57(18):4029-35      
Abrogation of an S-phase checkpoint and potentiation of camptothecin cytotoxicity by 7-hydroxystaurosporine (UCN-01) in human cancer cell lines, possibly influenced by p53 function.


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Gambacorti-Passerini C et

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Blood Cells Mol Dis 1997 Dec;23(3):380-94      
Inhibition of the ABL kinase activity blocks the proliferation of BCR/ABL+ leukemic cells and induces apoptosis.


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Tetsu O and McCormick F

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Nature 1999 Apr 1;398(6726):422-6      
Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells.


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Contreras JL et al

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Transplantation 1999 Jul 27;68(2):215-9      
Tolerability and side effects of anti-CD3-immunotoxin in preclinical testing in kidney and pancreatic islet transplant recipients.


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Cancer Res 1999 Nov 1;59(21):5483-7      
Mitogen-activated protein kinase kinase 4/stress-activated protein/Erk kinase 1 (MKK4/SEK1), a prostate cancer metastasis suppressor gene encoded by human chromosome 17.


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Broeks A et al

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Am J Hum Genet 2000 Feb;66(2):494-500      
ATM-heterozygous germline mutations contribute to breast cancer-susceptibility.


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Venter JC et al

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Science 2001 Feb 16;291(5507):1304-51      
The sequence of the human genome.


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Culmsee C et al

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J Neurochem 2001 Apr;77(1):220-8      
A synthetic inhibitor of p53 protects neurons against death induced by ischemic and excitotoxic insults, and amyloid beta-peptide.


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Pepe MS et al

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J Natl Cancer Inst 2001 Jul 18;93(14):1054-61      
Phases of biomarker development for early detection of cancer.


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Pedersen MW et al

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Ann Oncol 2001 Jun;12(6):745-60      
The type III epidermal growth factor receptor mutation. Biological significance and potential target for anti-cancer therapy.


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Sartippour MR et al

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Oncol Rep 2001 Nov-Dec;8(6):1355-7      
Livistona extract inhibits angiogenesis and cancer growth.


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Welsh CF et al

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Nat Cell Biol 2001 Nov;3(11):950-7      
Timing of cyclin D1 expression within G1 phase is controlled by Rho.


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Kim JH et al

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Osteopontin as a potential diagnostic biomarker for ovarian cancer.


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Li J et al

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Clin Chem 2002 Aug;48(8):1296-304      
Proteomics and bioinformatics approaches for identification of serum biomarkers to detect breast cancer.


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Kumar MS et al

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Structures of apolipoprotein A-II and a lipid-surrogate complex provide insights into apolipoprotein-lipid interactions.


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Grippo PJ et al

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Preinvasive pancreatic neoplasia of ductal phenotype induced by acinar cell targeting of mutant Kras in transgenic mice.


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Facile methods for generating human somatic cell gene knockouts using recombinant adeno-associated viruses.


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Hwang WS et al

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Evidence of a pluripotent human embryonic stem cell line derived from a cloned blastocyst.


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Merkelbach-Bruse S et al

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Su YH et al

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J Mol Diagn 2004 May;6(2):101-7      
Human urine contains small, 150 to 250 nucleotide-sized, soluble DNA derived from the circulation and may be useful in the detection of colorectal cancer.


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Mombaerts P et al

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Cell 1992 Mar 6;68(5):869-77      
RAG-1-deficient mice have no mature B and T lymphocytes.


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Darnton SJ et al

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Int J Cancer 2005 Jun 20;115(3):351-8      
Tissue inhibitor of metalloproteinase-3 (TIMP-3) gene is methylated in the development of esophageal adenocarcinoma: loss of expression correlates with poor prognosis.


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Zachara BA et al

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Neoplasma 2005;52(3):248-54      
Blood and tissue selenium concentrations and glutathione peroxidase activities in patients with prostate cancer and benign prostate hyperplasia.


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Zhang X et al

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Hum Mutat 2006 Jan;27(1):110-7      
Genetic polymorphisms in cell cycle regulatory genes MDM2 and TP53 are associated with susceptibility to lung cancer.


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Pagès F et al

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N Engl J Med 2005 Dec 22;353(25):2654-66      
Effector memory T cells, early metastasis, and survival in colorectal cancer.


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Won J et al

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Nat Chem Biol 2006 Jul;2(7):369-74      
Small molecule-based reversible reprogramming of cellular lifespan.


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Malik M et al

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Mol Cancer Ther 2006 Jun;5(6):1405-14      
Roles of nonhomologous end-joining pathways in surviving topoisomerase II-mediated DNA damage.


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Taylor NP et al

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Cancer Res 2006 Aug 1;66(15):7502-8      
MLH3 mutation in endometrial cancer.


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Dewan A et al

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Science 2006 Nov 10;314(5801):989-92      
HTRA1 promoter polymorphism in wet age-related macular degeneration.


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Souglakos J et al

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Dig Dis 2007;25(1):100-5      
Irinotecan plus weekly 5-fluorouracil and leucovorin as salvage treatment for patients with metastatic colorectal cancer: a phase II trial.


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Nat Genet 2007 May;39(5):645-9      
Genome-wide association study of prostate cancer identifies a second risk locus at 8q24.


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Stupp R and Hegi ME

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J Clin Oncol 2007 Apr 20;25(12):1459-60      
Methylguanine methyltransferase testing in glioblastoma: when and how?


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Mantzoros CS et al

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Eur J Cancer 2007 Jun;43(9):1430-6      
Circulating adiponectin levels in relation to melanoma: a case-control study.


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Mol Cell Biol 2007 Sep;27(17):6068-83      
Arkadia activates Smad3/Smad4-dependent transcription by triggering signal-induced SnoN degradation.


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Hao Y et al

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BMC Gastroenterol 2007 Jun 27;7:24      
Gene expression changes associated with Barrett's esophagus and Barrett's-associated adenocarcinoma cell lines after acid or bile salt exposure.


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Cancer Genomics Proteomic 2007 Jan-Feb;4(1):1-20      
Transcriptomic molecular markers for screening human colon cancer in stool and tissue.


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J Agric Food Chem 2007 Nov 14;55(23):9470-8      
Antiproliferative and apoptotic effects of chamomile extract in various human cancer cells.


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Lutsey PL et al

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Circulation 2008 Feb 12;117(6):754-61      
Dietary intake and the development of the metabolic syndrome: the Atherosclerosis Risk in Communities study.


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Cancer Res 2008 May 15;68(10):3558-60; di      
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Roy HK et al

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Dis Colon Rectum 2008 Sep;51(9):1381-6      
Spectral slope from the endoscopically-normal mucosa predicts concurrent colonic neoplasia: a pilot ex-vivo clinical study.


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Gynecol Oncol 2009 Jan;112(1):47-54      
A serum based analysis of ovarian epithelial tumorigenesis.


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Kasowski M et al

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Science 2010 Apr 9;328(5975):232-5      
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Schaeffer HJ et al

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9-(2-hydroxyethoxymethyl) guanine activity against viruses of the herpes group.


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Proc Natl Acad Sci U S A 2010 Dec 7;107(49):21098-103      
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Culler SJ et al

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Science 2010 Nov 26;330(6008):1251-5      
Reprogramming cellular behavior with RNA controllers responsive to endogenous proteins.


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Ceol CJ et al

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Nature 2011 Mar 24;471(7339):513-7      
The histone methyltransferase SETDB1 is recurrently amplified in melanoma and accelerates its onset.


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Nakamura T et al

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Molecular cloning and expression of human hepatocyte growth factor.


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Frequent detection and isolation of cytopathic retroviruses (HTLV-III) from patients with AIDS and at risk for AIDS.


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New calcium indicators and buffers with high selectivity against magnesium and protons: design, synthesis, and properties of prototype structures.


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A novel growth suppressor gene on chromosome 17p13.3 with a high frequency of mutation in human hepatocellular carcinoma.


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Authors represented in these publications:

Abraham D, Adams MD, Agelaki S, Ahmed FE, Alarcón C, Androulakis N, Arlotti J, Assoian RK, Azuma Y, Baba Y, Baccarini M, Bacchiocchi A, Backman V, Barnes PJ, Barnstable C, Barré-Sinoussi F, Baserga R, Bast RC Jr, Bauer DJ, Beauchamp L, Beer DG, Behar J, Belotti D, Berger A, Berkowitz RS, Bero LA, Bhattacharya B, Blasco MA, Blecharz-Klin K, Bloch-Boguslawska E, Block TM, Bodmer W, Boise LH, Bos PD, Braconi C, Brandt-Rauf P, Bray-Ward P, Breban M, Brenner DE, Brodsky JL, Broeks A, Brummond KM, Buchkovich KJ, Buga GM, Burgaud JL, Burrell M, Byrns RE, Büttner R, Cahalane S, Camus M, Cantley LC, Cao CX, Cao W, Capecchi MR, Carson M, Cartner S, Casson AG, Ceol CJ, Chan DW, Chang KY, Chanock SJ, Chaudhuri G, Chekmareva MA, Chermann JC, Choy ML, Christiano TR, Christofori G, Chrousos GP, Cibelli JB, Clarke R, Clift RA, Collins P, Contreras JL, Cramer DW, Croce CM, Culler SJ, Culmsee C, Daly L, Damstrup L, Daraio C, Darnton SJ, Das D, Davis RW, De Siervi A, DePinho RA, Demeure MJ, Dewan A, Dhir 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