_______________The Other 90% of Science_______________

Most Viewed




Califf RM et al

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N Engl J Med 1994 Apr 7;330(14):956-61      
Use of a monoclonal antibody directed against the platelet glycoprotein IIb/IIIa receptor in high-risk coronary angioplasty. The EPIC Investigation.


Lisitsyn N et al

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Science 1993 Feb 12;259(5097):946-51      
Cloning the differences between two complex genomes.


Pantaleo G et al

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Nature 1993 Mar 25;362(6418):355-8      
HIV infection is active and progressive in lymphoid tissue during the clinically latent stage of disease.


Nishihira T et al

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J Cancer Res Clin Oncol 1993;119(8):441-9      
Molecular and cellular features of esophageal cancer cells.


Arnold SF et al

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Science 1996 Jun 7;272(5267):1489-92      
Synergistic activation of estrogen receptor with combinations of environmental chemicals.


Thiagalingam A et al

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Mol Cell Biol 1996 Oct;16(10):5335-45      
RREB-1, a novel zinc finger protein, is involved in the differentiation response to Ras in human medullary thyroid carcinomas.


Gent M et al

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Lancet 1996 Nov 16;348(9038):1329-39      
A randomised, blinded, trial of clopidogrel versus aspirin in patients at risk of ischaemic events (CAPRIE). CAPRIE Steering Committee.


Steck PA et al

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Nat Genet 1997 Apr;15(4):356-62      
Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers.


Altschul SF et al

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Nucleic Acids Res 1997 Sep 1;25(17):3389-402      
Gapped BLAST and PSI-BLAST: a new generation of protein database search programs.


Sun J et al

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Oncogene 1998 Mar;16(11):1467-73      
Both farnesyltransferase and geranylgeranyltransferase I inhibitors are required for inhibition of oncogenic K-Ras prenylation but each alone is sufficient to suppress human tumor growth in nude mouse xenografts.


Gelband CH et al

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Hypertension 1999 Jan;33(1 Pt 2):360-5      
Angiotensin II type 1 receptor antisense gene therapy prevents altered renal vascular calcium homeostasis in hypertension.


Irby RB et al

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Nat Genet 1999 Feb;21(2):187-90      
Activating SRC mutation in a subset of advanced human colon cancers.


Koch R

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Meitteilungen Kais Gesund 1884      
Die Aetiologie der Tuberkulose


Brodie SJ et al

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Am J Pathol 1999 May;154(5):1453-64      
Pediatric AIDS-associated lymphocytic interstitial pneumonia and pulmonary arterio-occlusive disease: role of VCAM-1/VLA-4 adhesion pathway and human herpesviruses.


Cressman VL et al

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Mol Cell Biol 1999 Oct;19(10):7061-75      
Growth retardation, DNA repair defects, and lack of spermatogenesis in BRCA1-deficient mice.


Sallusto F et al

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Nature 1999 Oct 14;401(6754):708-12      
Two subsets of memory T lymphocytes with distinct homing potentials and effector functions.


Etheredge JA et al

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Proc Natl Acad Sci U S A 1999 Nov 23;96(24):13845-6      
Monarch butterflies (Danaus plexippus L.) use a magnetic compass for navigation.


Furuuchi K et al

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Am J Pathol 2000 Jun;156(6):1997-2005      
Somatic mutations of the APC gene in primary breast cancers.


Murthy KH et al

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Cell 2001 Jan 26;104(2):301-11      
Crystal structure of a complement control protein that regulates both pathways of complement activation and binds heparan sulfate proteoglycans.


Tissenbaum HA and Guarente L

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Nature 2001 Mar 8;410(6825):227-30      
Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans.


Culmsee C et al

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J Neurochem 2001 Apr;77(1):220-8      
A synthetic inhibitor of p53 protects neurons against death induced by ischemic and excitotoxic insults, and amyloid beta-peptide.


Sartippour MR et al

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Oncol Rep 2001 Nov-Dec;8(6):1355-7      
Livistona extract inhibits angiogenesis and cancer growth.


Welsh CF et al

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Nat Cell Biol 2001 Nov;3(11):950-7      
Timing of cyclin D1 expression within G1 phase is controlled by Rho.


Joe AK et al

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Clin Cancer Res 2002 Mar;8(3):893-903      
Resveratrol induces growth inhibition, S-phase arrest, apoptosis, and changes in biomarker expression in several human cancer cell lines.


Kim JH et al

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JAMA 2002 Apr 3;287(13):1671-9      
Osteopontin as a potential diagnostic biomarker for ovarian cancer.


Kumar MS et al

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Biochemistry 2002 Oct 1;41(39):11681-91      
Structures of apolipoprotein A-II and a lipid-surrogate complex provide insights into apolipoprotein-lipid interactions.


Nakajima M et al

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Br J Cancer 2003 Jun 2;88(11):1734-9      
Reduced expression of Axin correlates with tumour progression of oesophageal squamous cell carcinoma.


Roovers K and Assoian RK

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Mol Cell Biol 2003 Jun;23(12):4283-94      
Effects of rho kinase and actin stress fibers on sustained extracellular signal-regulated kinase activity and activation of G(1) phase cyclin-dependent kinases.


Gunther EC et al

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Proc Natl Acad Sci U S A 2003 Aug 5;100(16):9608-13      
Prediction of clinical drug efficacy by classification of drug-induced genomic expression profiles in vitro.


Furchgott RF and Bhadrakom S

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J Pharmacol Exp Ther 1953 Jun;108(2):129-43      
Reactions of strips of rabbit aorta to epinephrine, isopropylarterenol, sodium nitrite and other drugs.



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J Biol Chem 1962 May;237:1555-62      
Isolation of a mouse submaxillary gland protein accelerating incisor eruption and eyelid opening in the new-born animal.


Rodbell M

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J Biol Chem 1964 Feb;239:375-80      
Metabolism of isolated fat cells. I. Effects of hormones on glucose metabolism and lipolysis.


Kim AH et al

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Int J Oncol 2003 Dec;23(6):1593-9      
Transforming growth factor-beta is an endogenous radioresistance factor in the esophageal adenocarcinoma cell line OE-33.


Dhir R et al

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J Urol 2004 Apr;171(4):1419-23      
Early identification of individuals with prostate cancer in negative biopsies.


Ganesh VK et al

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Proc Natl Acad Sci U S A 2004 Jun 15;101(24):8924-9      
Structure of vaccinia complement protein in complex with heparin and potential implications for complement regulation.


Zheng L et al

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Nucleic Acids Res 2004 Aug 10;32(14):e115      
An efficient one-step site-directed and site-saturation mutagenesis protocol.


Jalili A et al

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Blood 2005 Nov 15;106(10):3538-45      
Induction of HM1.24 peptide-specific cytotoxic T lymphocytes by using peripheral-blood stem-cell harvests in patients with multiple myeloma.


Lane DP

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Nature 1992 Jul 2;358(6381):15-6      
Cancer. p53, guardian of the genome.


Kang Y et al

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Proc Natl Acad Sci U S A 2005 Sep 27;102(39):13909-14      
Breast cancer bone metastasis mediated by the Smad tumor suppressor pathway.


Honda K et al

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Cancer Res 2005 Nov 15;65(22):10613-22      
Possible detection of pancreatic cancer by plasma protein profiling.


Pagès F et al

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N Engl J Med 2005 Dec 22;353(25):2654-66      
Effector memory T cells, early metastasis, and survival in colorectal cancer.


Won J et al

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Nat Chem Biol 2006 Jul;2(7):369-74      
Small molecule-based reversible reprogramming of cellular lifespan.


Malik M et al

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Mol Cancer Ther 2006 Jun;5(6):1405-14      
Roles of nonhomologous end-joining pathways in surviving topoisomerase II-mediated DNA damage.


Suetsugu A et al

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Biochem Biophys Res Commu 2006 Dec 29;351(4):820-4      
Characterization of CD133+ hepatocellular carcinoma cells as cancer stem/progenitor cells.


Schüler M et al

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Nat Struct Mol Biol 2006 Dec;13(12):1092-6      
Structure of the ribosome-bound cricket paralysis virus IRES RNA.


Liu R et al

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N Engl J Med 2007 Jan 18;356(3):217-26      
The prognostic role of a gene signature from tumorigenic breast-cancer cells.


Bulanova E et al

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J Biol Chem 2007 May 4;282(18):13167-79      
Soluble Interleukin IL-15Ralpha is generated by alternative splicing or proteolytic cleavage and forms functional complexes with IL-15.


Yeager M et al

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Nat Genet 2007 May;39(5):645-9      
Genome-wide association study of prostate cancer identifies a second risk locus at 8q24.


Levy L et al

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Mol Cell Biol 2007 Sep;27(17):6068-83      
Arkadia activates Smad3/Smad4-dependent transcription by triggering signal-induced SnoN degradation.


Hao Y et al

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BMC Gastroenterol 2007 Jun 27;7:24      
Gene expression changes associated with Barrett's esophagus and Barrett's-associated adenocarcinoma cell lines after acid or bile salt exposure.


Pfeiffer T and Hoffmann R

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Proc Natl Acad Sci U S A 2007 Jul 17;104(29):12052-6      
Temporal patterns of genes in scientific publications.


Ahmed FE et al

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Cancer Genomics Proteomic 2007 Jan-Feb;4(1):1-20      
Transcriptomic molecular markers for screening human colon cancer in stool and tissue.


Srivastava JK and Gupta S

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J Agric Food Chem 2007 Nov 14;55(23):9470-8      
Antiproliferative and apoptotic effects of chamomile extract in various human cancer cells.


Jin Z et al

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Clin Cancer Res 2007 Nov 1;13(21):6293-300      
Hypermethylation of tachykinin-1 is a potential biomarker in human esophageal cancer.


Tsai J et al

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Proc Natl Acad Sci U S A 2008 Feb 26;105(8):3041-6      
Discovery of a selective inhibitor of oncogenic B-Raf kinase with potent antimelanoma activity.


Ogunwobi OO and Beales IL

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Mol Cell Endocrinol 2008 Mar 26;285(1-2):43-50      
Globular adiponectin, acting via adiponectin receptor-1, inhibits leptin-stimulated oesophageal adenocarcinoma cell proliferation.


van Dekken H et al

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Genes Chromosomes Cancer 2008 Aug;47(8):649-56      
Molecular dissection of the chromosome band 7q21 amplicon in gastroesophageal junction adenocarcinomas identifies cyclin-dependent kinase 6 at both genomic and protein expression levels.


van Rooij E et al

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Proc Natl Acad Sci U S A 2008 Sep 2;105(35):13027-32      
Dysregulation of microRNAs after myocardial infarction reveals a role of miR-29 in cardiac fibrosis.


Peters U and Takata Y

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Mol Nutr Food Res 2008 Nov;52(11):1261-72      
Selenium and the prevention of prostate and colorectal cancer.


Garman KS et al

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Proc Natl Acad Sci U S A 2008 Dec 9;105(49):19432-7      
A genomic approach to colon cancer risk stratification yields biologic insights into therapeutic opportunities.


Waldman SA et al

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JAMA 2009 Feb 18;301(7):745-52      
Association of GUCY2C expression in lymph nodes with time to recurrence and disease-free survival in pN0 colorectal cancer.


Blecharz-Klin K et al

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Acta Neurobiol Exp (Wars) 2009;69(2):217-31      
Pharmacological and biochemical effects of Ginkgo biloba extract on learning, memory consolidation and motor activity in old rats.


Alberts B

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Science 2009 Nov 27;326(5957):1163      
On incentives for innovation.


Carson WE 3rd et al

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J Immunother (1991) 1991 Apr;10(2):131-40      
Rat mitogen-stimulated lymphokine-activated T killer cells: production and effects on C6 glioma cells in vitro and in vivo in the brain of Wistar rats.


Hockenbery D et al

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Nature 1990 Nov 22;348(6299):334-6      
Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death.


Lippincott-Schwartz J et al

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Cell 1989 Mar 10;56(5):801-13      
Rapid redistribution of Golgi proteins into the ER in cells treated with brefeldin A: evidence for membrane cycling from Golgi to ER.


Sanger F et al

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Proc Natl Acad Sci U S A 1977 Dec;74(12):5463-7      
DNA sequencing with chain-terminating inhibitors.


Oesch B et al

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Cell 1985 Apr;40(4):735-46      
A cellular gene encodes scrapie PrP 27-30 protein.


Katada T et al

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Eur J Biochem 1985 Sep 2;151(2):431-7      
Protein kinase C phosphorylates the inhibitory guanine-nucleotide-binding regulatory component and apparently suppresses its function in hormonal inhibition of adenylate cyclase.


Schwarz RE et al

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J Immunol 1988 Nov 15;141(10):3318-23      
The expression and functional involvement of laminin-like molecules in non-MHC restricted cytotoxicity by human Leu-19+/CD3- natural killer lymphocytes.


Storb R et al

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N Engl J Med 1986 Mar 20;314(12):729-35      
Methotrexate and cyclosporine compared with cyclosporine alone for prophylaxis of acute graft versus host disease after marrow transplantation for leukemia.


Zinkernagel RM and Doherty PC

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Nature 1974 Apr 19;248(450):701-2      
Restriction of in vitro T cell-mediated cytotoxicity in lymphocytic choriomeningitis within a syngeneic or semiallogeneic system.


Salomon Y et al

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Anal Biochem 1974 Apr;58(2):541-8      
A highly sensitive adenylate cyclase assay.


Thor A et al

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Nature 1984 Oct 11-17;311(5986):562-5      
Monoclonal antibodies define differential ras gene expression in malignant and benign colonic diseases.


Brenner MK et al

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Lancet 1993 Jan 9;341(8837):85-6      
Gene-marking to trace origin of relapse after autologous bone-marrow transplantation.


Wijmenga C et al

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Proc Natl Acad Sci U S A 1996 Feb 20;93(4):1630-5      
Core binding factor beta-smooth muscle myosin heavy chain chimeric protein involved in acute myeloid leukemia forms unusual nuclear rod-like structures in transformed NIH 3T3 cells.


Kanowski S et al

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Pharmacopsychiatry 1996 Mar;29(2):47-56      
Proof of efficacy of the ginkgo biloba special extract EGb 761 in outpatients suffering from mild to moderate primary degenerative dementia of the Alzheimer type or multi-infarct dementia.


Ostareck DH et al

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Cell 1997 May 16;89(4):597-606      
mRNA silencing in erythroid differentiation: hnRNP K and hnRNP E1 regulate 15-lipoxygenase translation from the 3' end.


Ehrlich P and Morgenroth J

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Berlin Klin Wochenschrift 1900; 37:453-458      
Ueber Haemolysine: dritte Mittheilung.


Tetsu O and McCormick F

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Nature 1999 Apr 1;398(6726):422-6      
Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells.


Kleeff J et al

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Gastroenterology 1999 May;116(5):1202-16      
Bone morphogenetic protein 2 exerts diverse effects on cell growth in vitro and is expressed in human pancreatic cancer in vivo.


Croce CM et al

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J Clin Oncol 1999 May;17(5):1618-24      
Role of FHIT in human cancer.


Takeuchi O et al

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Immunity 1999 Oct;11(4):443-51      
Differential roles of TLR2 and TLR4 in recognition of gram-negative and gram-positive bacterial cell wall components.


Handa A et al

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J Gen Virol 2000 Aug;81(Pt 8):2077-84      
Adeno-associated virus (AAV)-3-based vectors transduce haematopoietic cells not susceptible to transduction with AAV-2-based vectors.


Smith T et al

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J Biol Chem 2000 Dec 22;275(51):40407-15      
Arachidonic acid and nonsteroidal anti-inflammatory drugs induce conformational changes in the human prostaglandin endoperoxide H2 synthase-2 (cyclooxygenase-2).


Tascilar M et al

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Clin Cancer Res 2001 Dec;7(12):4115-21      
The SMAD4 protein and prognosis of pancreatic ductal adenocarcinoma.


Van Den Bosch L et al

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Neuroreport 2002 Jun 12;13(8):1067-70      
Minocycline delays disease onset and mortality in a transgenic model of ALS.


Vassileva V et al

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Cancer Res 2002 Jul 15;62(14):4095-9      
Genes involved in DNA repair are mutational targets in endometrial cancers with microsatellite instability.


Lo HS et al

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Cancer Res 2002 Aug 1;62(15):4191-3      
Identification of somatic mutations of the RNF6 gene in human esophageal squamous cell carcinoma.


Dennis JL et al

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Cancer Res 2002 Nov 1;62(21):5999-6005      
Identification from public data of molecular markers of adenocarcinoma characteristic of the site of origin.


Villar-Garea A et al

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Cancer Res 2003 Aug 15;63(16):4984-9      
Procaine is a DNA-demethylating agent with growth-inhibitory effects in human cancer cells.


Aguirre AJ et al

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Genes Dev 2003 Dec 15;17(24):3112-26      
Activated Kras and Ink4a/Arf deficiency cooperate to produce metastatic pancreatic ductal adenocarcinoma.


Cunningham SC et al

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Biotechniques 2004 Jul;37(1):120-2      
Nonspecific enhancement of gene expression by compounds identified in high-throughput cell-based screening.


Emami KH et al

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Proc Natl Acad Sci U S A 2004 Aug 24;101(34):12682-7      
A small molecule inhibitor of beta-catenin/CREB-binding protein transcription [corrected].


Yu JK et al

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World J Gastroenterol 2004 Nov 1;10(21):3127-31      
An integrated approach to the detection of colorectal cancer utilizing proteomics and bioinformatics.


Darnton SJ et al

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Int J Cancer 2005 Jun 20;115(3):351-8      
Tissue inhibitor of metalloproteinase-3 (TIMP-3) gene is methylated in the development of esophageal adenocarcinoma: loss of expression correlates with poor prognosis.


Ivancsits S et al

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Mutat Res 2005 Jun 6;583(2):184-8      
Cell type-specific genotoxic effects of intermittent extremely low-frequency electromagnetic fields.


Hwang WS et al

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Science 2005 Jun 17;308(5729):1777-83      
Patient-specific embryonic stem cells derived from human SCNT blastocysts.


Glinsky GV et al

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J Clin Invest 2005 Jun;115(6):1503-21      
Microarray analysis identifies a death-from-cancer signature predicting therapy failure in patients with multiple types of cancer.


Sarosi GA Jr et al

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Am J Physiol Gastrointest 2005 Dec;289(6):G991-7      
Acid increases MAPK-mediated proliferation in Barrett's esophageal adenocarcinoma cells via intracellular acidification through a Cl-/HCO3- exchanger.

Authors represented in these publications:

Abe M, Abraham JM, Acharya CR, Aguirre AJ, Ahmed FE, Akira S, Alberts B, Altschul SF, Anderson WF, Aoki H, Arlotti J, Arnold SF, Artis DR, Assoian RK, Avrutskaya AV, BHADRAKOM S, Backlund DC, Ball DW, Bapat B, Bardeesy N, Barlow PN, Bauer S, Baumann U, Baylin SB, Beales IL, Beaumont D, Beckman MT, Beer DG, Bento P, Berezovska O, Berger A, Berkowitz RS, Blanchard J, Blasberg R, Blecharz-Klin K, Bollag G, Bonaccorso C, Bonifacino JS, Borges M, Brenner MK, Briollais L, Brodie SJ, Brown KE, Budagian V, Bulanova E, Bulfone-Paus S, Büchler MW, CALIFF RM, COHEN S, Camus M, Carson M, Carson WE 3rd, Caruso A, Casson AG, Chang KY, Chanock SJ, Chapman W, Chen GY, Chen YD, Chung TD, Clarke MF, Collins BM, Collins FS, Connell SR, Coppola D, Coulson AR, Cramer DW, Cressman VL, Croce CM, Crouch J, Culmsee C, Cunningham SC, Darnton SJ, Das D, De Bustros A, DePinho RA, DeWitt D, Deeg HJ, Demarest JF, Dennis JL, Dhir R, Diem E, Diem K, Dietz CM, Doherty PC, Duitman E, Dulkanchainun S, Edelman E, Ehrlich P, Eils R, Eley KW, Emami KH, Enriquez-Rios V, Episkopou V, Espada J, Esteller M, Etheredge JA, Evans J, FURCHGOTT RF, Fauci AS, Fraga MF, Fridman WH, Friess H, Fujita DJ, Fukuchi M, Furuuchi K, Förster R, GATES K, Galon J, Ganesh VK, Garman KS, Gelband CH, Gent M, Gerald WL, Gere S, Gerwien RW, Getzenberg RH, Gilman AG, Glinskii AB, Glinsky GV, Go VL, Godfrey V, Goggins M, Goldstein AM, Granger GA, Graziosi C, Gregory PE, Greig NH, Guarente L, Guillette LJ Jr, Gunther EC, Guo Z, Gupta S, Ha JR, Hajra A, Hamilton AD, Handa A, Hao Y, Hara T, Hardie LJ, Harkin S, Hashimoto Y, Hayashida Y, Hayes RB, He W, Heber D, Hentze MW, Herlyn M, Herndon E, Herrmann WM, Heyes MP, Hill CS, Hill JA, Hirohashi S, Hiserodt JC, Hockenbery D, Hoffmann R, Honda K, Hood LE, Horan Hand P, Horner J, Hoshino K, Howe JG, Howell M, Hruban RH, Hsu D, Hu N, Huebner K, Hunter DJ, Hussain MM, Hwang WS, Hyslop T, Hörr R, Ihle JN, Irby RB, Ishiwata T, Ivancsits S, Jahn O, Jaiswal K, Jakobs KH, Jakowatz JG, Jalili 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