_______________The Other 90% of Science_______________

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Arichi T et al

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Proc Natl Acad Sci U S A 2000 Jan 4;97(1):297-302      
Prophylactic DNA vaccine for hepatitis C virus (HCV) infection: HCV-specific cytotoxic T lymphocyte induction and protection from HCV-recombinant vaccinia infection in an HLA-A2.1 transgenic mouse model.


Finch JT and Klug A

ViewRank: 502
Proc Natl Acad Sci U S A 1976 Jun;73(6):1897-901      
Solenoidal model for superstructure in chromatin.


Chadwick RB et al

ViewRank: 503
Proc Natl Acad Sci U S A 2000 Mar 14;97(6):2662-7      
Candidate tumor suppressor RIZ is frequently involved in colorectal carcinogenesis.


Tchernof A et al

ViewRank: 504
Diabetes Metab 2000 Feb;26(1):12-20      
Body fat distribution, the menopause transition, and hormone replacement therapy.


Furuuchi K et al

ViewRank: 505
Am J Pathol 2000 Jun;156(6):1997-2005      
Somatic mutations of the APC gene in primary breast cancers.


Smith T et al

ViewRank: 506
J Biol Chem 2000 Dec 22;275(51):40407-15      
Arachidonic acid and nonsteroidal anti-inflammatory drugs induce conformational changes in the human prostaglandin endoperoxide H2 synthase-2 (cyclooxygenase-2).


Bombardier C et al

ViewRank: 507
N Engl J Med 2000 Nov 23;343(21):1520-8, 2       
Comparison of upper gastrointestinal toxicity of rofecoxib and naproxen in patients with rheumatoid arthritis. VIGOR Study Group.


Wagner M et al

ViewRank: 508
Genes Dev 2001 Feb 1;15(3):286-93      
A murine tumor progression model for pancreatic cancer recapitulating the genetic alterations of the human disease.


Hedenfalk I et al

ViewRank: 509
N Engl J Med 2001 Feb 22;344(8):539-48      
Gene-expression profiles in hereditary breast cancer.


Arango D et al

ViewRank: 510
Cancer Res 2001 Jun 15;61(12):4910-5      
c-myc/p53 interaction determines sensitivity of human colon carcinoma cells to 5-fluorouracil in vitro and in vivo.


Giannini G et al

ViewRank: 511
EMBO Rep 2002 Mar;3(3):248-54      
Human MRE11 is inactivated in mismatch repair-deficient cancers.


Joe AK et al

ViewRank: 512
Clin Cancer Res 2002 Mar;8(3):893-903      
Resveratrol induces growth inhibition, S-phase arrest, apoptosis, and changes in biomarker expression in several human cancer cell lines.


Qu Y et al

ViewRank: 513
Clin Chem 2002 Oct;48(10):1835-43      
Boosted decision tree analysis of surface-enhanced laser desorption/ionization mass spectral serum profiles discriminates prostate cancer from noncancer patients.


Niessing D et al

ViewRank: 514
Genes Dev 2002 Oct 1;16(19):2576-82      
Bicoid associates with the 5'-cap-bound complex of caudal mRNA and represses translation.


Dennis JL et al

ViewRank: 515
Cancer Res 2002 Nov 1;62(21):5999-6005      
Identification from public data of molecular markers of adenocarcinoma characteristic of the site of origin.


Tentori L et al

ViewRank: 516
Mol Pharmacol 2003 Jan;63(1):192-202      
Inhibition of telomerase increases resistance of melanoma cells to temozolomide, but not to temozolomide combined with poly (adp-ribose) polymerase inhibitor.


Wong JM et al

ViewRank: 517
Oncogene 2003 Jan 9;22(1):28-33      
Interaction between BRCA2 and replication protein A is compromised by a cancer-predisposing mutation in BRCA2.


Nakajima M et al

ViewRank: 518
Br J Cancer 2003 Jun 2;88(11):1734-9      
Reduced expression of Axin correlates with tumour progression of oesophageal squamous cell carcinoma.


Chiriva-Internati M et al

ViewRank: 519
Blood 2003 Nov 1;102(9):3100-7      
Testing recombinant adeno-associated virus-gene loading of dendritic cells for generating potent cytotoxic T lymphocytes against a prototype self-antigen, multiple myeloma HM1.24.


Gunther EC et al

ViewRank: 520
Proc Natl Acad Sci U S A 2003 Aug 5;100(16):9608-13      
Prediction of clinical drug efficacy by classification of drug-induced genomic expression profiles in vitro.


Howitz KT et al

ViewRank: 521
Nature 2003 Sep 11;425(6954):191-6      
Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan.


Inaba K et al

ViewRank: 522
J Exp Med 1992 Dec 1;176(6):1693-702      
Generation of large numbers of dendritic cells from mouse bone marrow cultures supplemented with granulocyte/macrophage colony-stimulating factor.


Kajinami K et al

ViewRank: 523
Am J Cardiol 2004 Jan 1;93(1):104-7      
CYP3A4 genotypes and plasma lipoprotein levels before and after treatment with atorvastatin in primary hypercholesterolemia.


Kohli M et al

ViewRank: 524
Nucleic Acids Res 2004 Jan 2;32(1):e3      
Facile methods for generating human somatic cell gene knockouts using recombinant adeno-associated viruses.


Shichinohe H et al

ViewRank: 525
Brain Res 2004 Mar 19;1001(1-2):51-9      
FK506 reduces infarct volume due to permanent focal cerebral ischemia by maintaining BAD turnover and inhibiting cytochrome c release.


Cunningham SC et al

ViewRank: 526
Biotechniques 2004 Jul;37(1):120-2      
Nonspecific enhancement of gene expression by compounds identified in high-throughput cell-based screening.


Zheng L et al

ViewRank: 527
Nucleic Acids Res 2004 Aug 10;32(14):e115      
An efficient one-step site-directed and site-saturation mutagenesis protocol.


Emami KH et al

ViewRank: 528
Proc Natl Acad Sci U S A 2004 Aug 24;101(34):12682-7      
A small molecule inhibitor of beta-catenin/CREB-binding protein transcription [corrected].


Tiwari S et al

ViewRank: 529
Biochem Pharmacol 2005 Feb 1;69(3):473-83      
Type 4 cAMP phosphodiesterase (PDE4) inhibitors augment glucocorticoid-mediated apoptosis in B cell chronic lymphocytic leukemia (B-CLL) in the absence of exogenous adenylyl cyclase stimulation.


Zachara BA et al

ViewRank: 530
Neoplasma 2005;52(3):248-54      
Blood and tissue selenium concentrations and glutathione peroxidase activities in patients with prostate cancer and benign prostate hyperplasia.


Hwang WS et al

ViewRank: 531
Science 2005 Jun 17;308(5729):1777-83      
Patient-specific embryonic stem cells derived from human SCNT blastocysts.


Sarosi GA Jr et al

ViewRank: 532
Am J Physiol Gastrointest 2005 Dec;289(6):G991-7      
Acid increases MAPK-mediated proliferation in Barrett's esophageal adenocarcinoma cells via intracellular acidification through a Cl-/HCO3- exchanger.


Michl J et al

ViewRank: 533
Int J Cancer 2006 Oct 1;119(7):1577-85      
PNC-28, a p53-derived peptide that is cytotoxic to cancer cells, blocks pancreatic cancer cell growth in vivo.


Hao Y et al

ViewRank: 534
Gastroenterology 2006 Sep;131(3):925-33      
Gene expression profiling reveals stromal genes expressed in common between Barrett's esophagus and adenocarcinoma.


Mozaffarian D and Rimm EB

ViewRank: 535
JAMA 2006 Oct 18;296(15):1885-99      
Fish intake, contaminants, and human health: evaluating the risks and the benefits.


Bao S et al

ViewRank: 536
Nature 2006 Dec 7;444(7120):756-60      
Glioma stem cells promote radioresistance by preferential activation of the DNA damage response.


Rasheed WK et al

ViewRank: 537
Expert Opin Investig Drug 2007 May;16(5):659-78      
Histone deacetylase inhibitors in cancer therapy.


Batista LF et al

ViewRank: 538
Cancer Res 2007 Dec 15;67(24):11886-95      
Differential sensitivity of malignant glioma cells to methylating and chloroethylating anticancer drugs: p53 determines the switch by regulating xpc, ddb2, and DNA double-strand breaks.


Evers B et al

ViewRank: 539
Clin Cancer Res 2008 Jun 15;14(12):3916-25      
Selective inhibition of BRCA2-deficient mammary tumor cell growth by AZD2281 and cisplatin.


Garman KS et al

ViewRank: 540
Proc Natl Acad Sci U S A 2008 Dec 9;105(49):19432-7      
A genomic approach to colon cancer risk stratification yields biologic insights into therapeutic opportunities.


Hollstein M et al

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Science 1991 Jul 5;253(5015):49-53      
p53 mutations in human cancers.


Cavallari I et al

ViewRank: 542
Genes Chromosomes Cancer 2009 May;48(5):383-96      
Decreased expression and promoter methylation of the menin tumor suppressor in pancreatic ductal adenocarcinoma.


Rajeshkumar NV et al

ViewRank: 543
Clin Cancer Res 2009 Jun 15;15(12):4138-46      
Antitumor effects and biomarkers of activity of AZD0530, a Src inhibitor, in pancreatic cancer.


Sarafraz-Yazdi E et al

ViewRank: 544
Proc Natl Acad Sci U S A 2010 Feb 2;107(5):1918-23      
Anticancer peptide PNC-27 adopts an HDM-2-binding conformation and kills cancer cells by binding to HDM-2 in their membranes.


Ong CW et al

ViewRank: 545
Mod Pathol 2010 Mar;23(3):450-7      
CD133 expression predicts for non-response to chemotherapy in colorectal cancer.


Liu CC et al

ViewRank: 546
Proc Natl Acad Sci U S A 2010 Mar 16;107(11):5136-41      
LRP6 overexpression defines a class of breast cancer subtype and is a target for therapy.


Rajagopalan S et al

ViewRank: 547
Proc Natl Acad Sci U S A 2010 May 11;107(19):8587-92      
Mapping the physical and functional interactions between the tumor suppressors p53 and BRCA2.


Schaeffer HJ et al

ViewRank: 548
Nature 1978 Apr 13;272(5654):583-5      
9-(2-hydroxyethoxymethyl) guanine activity against viruses of the herpes group.


Forman D et al

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BMJ 1991 Jun 1;302(6788):1302-5      
Association between infection with Helicobacter pylori and risk of gastric cancer: evidence from a prospective investigation.


Wang Q et al

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Proc Natl Acad Sci U S A 2011 Feb 8;108(6):2444-9      
Mutant proteins as cancer-specific biomarkers.


Finlay CA et al

ViewRank: 551
Mol Cell Biol 1988 Feb;8(2):531-9      
Activating mutations for transformation by p53 produce a gene product that forms an hsc70-p53 complex with an altered half-life.


DeCaprio JA et al

ViewRank: 552
Cell 1988 Jul 15;54(2):275-83      
SV40 large tumor antigen forms a specific complex with the product of the retinoblastoma susceptibility gene.


Katada T et al

ViewRank: 553
Eur J Biochem 1985 Sep 2;151(2):431-7      
Protein kinase C phosphorylates the inhibitory guanine-nucleotide-binding regulatory component and apparently suppresses its function in hormonal inhibition of adenylate cyclase.


Thoma F et al

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J Cell Biol 1979 Nov;83(2 Pt 1):403-27      
Involvement of histone H1 in the organization of the nucleosome and of the salt-dependent superstructures of chromatin.


Guerrier-Takada C et al

ViewRank: 555
Cell 1983 Dec;35(3 Pt 2):849-57      
The RNA moiety of ribonuclease P is the catalytic subunit of the enzyme.


Walker JE et al

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EMBO J 1982;1(8):945-51      
Distantly related sequences in the alpha- and beta-subunits of ATP synthase, myosin, kinases and other ATP-requiring enzymes and a common nucleotide binding fold.


Schwab M et al

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Nature 1983 Sep 15-21;305(5931):245-8      
Amplified DNA with limited homology to myc cellular oncogene is shared by human neuroblastoma cell lines and a neuroblastoma tumour.


Kägi D et al

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Science 1994 Jul 22;265(5171):528-30      
Fas and perforin pathways as major mechanisms of T cell-mediated cytotoxicity.


Wrana JL et al

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Nature 1994 Aug 4;370(6488):341-7      
Mechanism of activation of the TGF-beta receptor.


Abrahams JP et al

ViewRank: 560
Nature 1994 Aug 25;370(6491):621-8      
Structure at 2.8 A resolution of F1-ATPase from bovine heart mitochondria.


Johnson TR et al

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Indian J Biochem Biophys 1994 Feb;31(1):1-13      
Gene therapy of rat brain glioblastoma by an episome-based transcriptional cassette expressing antisense IGF-I cDNA.


Resnicoff M et al

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Cancer Res 1994 Apr 15;54(8):2218-22      
Rat glioblastoma cells expressing an antisense RNA to the insulin-like growth factor-1 (IGF-1) receptor are nontumorigenic and induce regression of wild-type tumors.


Dockery DW et al

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N Engl J Med 1993 Dec 9;329(24):1753-9      
An association between air pollution and mortality in six U.S. cities.


Pantaleo G et al

ViewRank: 564
Nature 1993 Mar 25;362(6418):355-8      
HIV infection is active and progressive in lymphoid tissue during the clinically latent stage of disease.


Bischoff JR et al

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Science 1996 Oct 18;274(5286):373-6      
An adenovirus mutant that replicates selectively in p53-deficient human tumor cells.


Liaw D et al

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Nat Genet 1997 May;16(1):64-7      
Germline mutations of the PTEN gene in Cowden disease, an inherited breast and thyroid cancer syndrome.


Ostareck DH et al

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Cell 1997 May 16;89(4):597-606      
mRNA silencing in erythroid differentiation: hnRNP K and hnRNP E1 regulate 15-lipoxygenase translation from the 3' end.


Yingling JM et al

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Mol Cell Biol 1997 Dec;17(12):7019-28      
Tumor suppressor Smad4 is a transforming growth factor beta-inducible DNA binding protein.


Gambacorti-Passerini C et

ViewRank: 569
Blood Cells Mol Dis 1997 Dec;23(3):380-94      
Inhibition of the ABL kinase activity blocks the proliferation of BCR/ABL+ leukemic cells and induces apoptosis.


Gelband CH et al

ViewRank: 570
Hypertension 1999 Jan;33(1 Pt 2):360-5      
Angiotensin II type 1 receptor antisense gene therapy prevents altered renal vascular calcium homeostasis in hypertension.


Ehrlich P and Morgenroth J

ViewRank: 571
Berlin Klin Wochenschrift 1900; 37:453-458      
Ueber Haemolysine: dritte Mittheilung.


Jayachandra S et al

ViewRank: 572
Proc Natl Acad Sci U S A 1999 Sep 28;96(20):11566-71      
Three unrelated viral transforming proteins (vIRF, EBNA2, and E1A) induce the MYC oncogene through the interferon-responsive PRF element by using different transcription coadaptors.


Van Parijs L et al

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Immunity 1999 Sep;11(3):281-8      
Uncoupling IL-2 signals that regulate T cell proliferation, survival, and Fas-mediated activation-induced cell death.


Ruggiero KM and Marx DM

ViewRank: 574
J Pers Soc Psychol 1999 Oct;77(4):774-84      
Less pain and more to gain: why high-status group members blame their failure on discrimination.


Zhou Z et al

ViewRank: 575
Clin Immunol 2000 Nov;97(2):171-81      
On the origin of surface proteinase 3 of nonmyeloid cells: evidence favoring an exogenous source.


Seggerson K et al

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Dev Biol 2002 Mar 15;243(2):215-25      
Two genetic circuits repress the Caenorhabditis elegans heterochronic gene lin-28 after translation initiation.


Spruck CH et al

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Cancer Res 2002 Aug 15;62(16):4535-9      
hCDC4 gene mutations in endometrial cancer.


Shamim W et al

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N Engl J Med 2002 Oct 24;347(17):1326-33      
Nonsurgical reduction of the interventricular septum in patients with hypertrophic cardiomyopathy.


Sperber K et al

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J Immunol 2003 Feb 1;170(3):1566-78      
Induction of apoptosis by HIV-1-infected monocytic cells.


Cui H et al

ViewRank: 580
Science 2003 Mar 14;299(5613):1753-5      
Loss of IGF2 imprinting: a potential marker of colorectal cancer risk.


Roovers K and Assoian RK

ViewRank: 581
Mol Cell Biol 2003 Jun;23(12):4283-94      
Effects of rho kinase and actin stress fibers on sustained extracellular signal-regulated kinase activity and activation of G(1) phase cyclin-dependent kinases.



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J Biol Chem 1962 May;237:1555-62      
Isolation of a mouse submaxillary gland protein accelerating incisor eruption and eyelid opening in the new-born animal.


Furuichi Y et al

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J Cereb Blood Flow Metab 2003 Oct;23(10):1183-94      
Tacrolimus, a potential neuroprotective agent, ameliorates ischemic brain damage and neurologic deficits after focal cerebral ischemia in nonhuman primates.


Klivenyi P et al

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J Neurochem 2004 Feb;88(3):576-82      
Additive neuroprotective effects of creatine and cyclooxygenase 2 inhibitors in a transgenic mouse model of amyotrophic lateral sclerosis.


Zhao W et al

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Oncogene 2004 Jan 15;23(2):395-402      
Identification of Krüppel-like factor 4 as a potential tumor suppressor gene in colorectal cancer.


Dhir R et al

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J Urol 2004 Apr;171(4):1419-23      
Early identification of individuals with prostate cancer in negative biopsies.


Osafune T et al

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Anal Sci 2004 Jun;20(6):971-4      
Influence of the pH on separating DNA by high-speed microchip electrophoresis.


Vona-Davis L et al

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J Surg Res 2005 Jul 1;127(1):53-8      
MAPK and PI3K inhibition reduces proliferation of Barrett's adenocarcinoma in vitro.


Gu P et al

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Mol Cell Biol 2005 Oct;25(19):8507-19      
Orphan nuclear receptor GCNF is required for the repression of pluripotency genes during retinoic acid-induced embryonic stem cell differentiation.


Hede K

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J Natl Cancer Inst 2005 Sep 21;97(18):1324-5      
$104 million proteomics initiative gets green light.


Viswanathan M et al

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Dev Cell 2005 Nov;9(5):605-15      
A role for SIR-2.1 regulation of ER stress response genes in determining C. elegans life span.


Honda K et al

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Cancer Res 2005 Nov 15;65(22):10613-22      
Possible detection of pancreatic cancer by plasma protein profiling.


Chekulaeva M et al

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Cell 2006 Feb 10;124(3):521-33      
Bruno acts as a dual repressor of oskar translation, promoting mRNA oligomerization and formation of silencing particles.


Souglakos J et al

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Dig Dis 2007;25(1):100-5      
Irinotecan plus weekly 5-fluorouracil and leucovorin as salvage treatment for patients with metastatic colorectal cancer: a phase II trial.


Chao KS

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Semin Oncol 2007 Apr;34(2 Suppl 1):S31-6      
3'-deoxy-3'-(18)F-fluorothymidine (FLT) positron emission tomography for early prediction of response to chemoradiotherapy--a clinical application model of esophageal cancer.


Behera BC et al

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Phytother Res 2007 Dec;21(12):1159-70      
Tissue culture of some lichens and screening of their antioxidant, antityrosinase and antibacterial properties.


Schatton T et al

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Nature 2008 Jan 17;451(7176):345-9      
Identification of cells initiating human melanomas.


Ogunwobi OO and Beales IL

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Mol Cell Endocrinol 2008 Mar 26;285(1-2):43-50      
Globular adiponectin, acting via adiponectin receptor-1, inhibits leptin-stimulated oesophageal adenocarcinoma cell proliferation.


Montesano R et al

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Cell 1991 Nov 29;67(5):901-8      
Identification of a fibroblast-derived epithelial morphogen as hepatocyte growth factor.


Li J et al

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Nat Med 2008 May;14(5):579-84      
Replacing PCR with COLD-PCR enriches variant DNA sequences and redefines the sensitivity of genetic testing.

Authors represented in these publications:

Abbas AK, Abrahams JP, Abumiya T, Acharya CR, Adam BL, Adler G, Adler V, Agelaki S, Alitalo K, Altman S, Ambrose D, Andreeva A, Androulakis N, Anthony DD, Arango D, Arichi T, Arlotti J, Assoian RK, Attisano L, Augenlicht LH, Baba Y, Babbin BA, Baltimore D, Bao S, Barbarino M, Barlogie B, Baserga R, Batista LF, Bauer DJ, Bauer S, Baumann U, Beal MF, Beales IL, Beauchamp L, Behera BC, Belotti D, Bennington GA, Bento P, Berbeco R, Berdichevsky A, Berzofsky JA, Beuria P, Bigner DD, Bischoff JR, Bitterman KJ, Bittner M, Blanke S, Bloch-Boguslawska E, Bombardier C, Bowne WB, Brandt-Rauf P, Brodeur G, Brousseau ME, Bu G, COHEN S, Calingasan NY, Catalano PJ, Cavallari I, Cerignoli F, Chadwick RB, Chaerkady R, Chang Y, Chao KS, Chekulaeva M, Chen H, Chiriva-Internati M, Christmann M, Chung AC, Ciminale V, Coats AJ, Cohen HY, Collins P, Cooney AJ, Corner GA, Cortes P, Cruz-Correa M, Cui H, Cunningham C, Cunningham SC, D'Agostino DM, Datto MB, De Oliveira E, DeCaprio JA, DeWitt D, Demarest JF, Dennis JL, Després JP, Dewhirst MW, Dhir R, Dionne A, Dockery DW, Dong H, Drost R, Edelman E, Ehrlich P, Elion GB, Eliyahu D, Emami KH, Eng C, Engelhard VH, Ephrussi A, Epstein PM, Esposito G, Evans J, Evers B, Fattaey A, Fauci AS, Fay ME, Feinberg AP, Feinstone SM, Feng Z, Ferris BG Jr, Fersht AR, Figge J, Finch JT, Fine RL, Finlay CA, Flather M, Forman D, Frank MH, Frank NY, Frankenberry K, Frati L, Frederick JP, Fukuchi M, Fullerton F, Furuichi Y, Furuuchi K, Gambacorti-Passerini C, Gardian G, Gardiner K, Garman KS, Gay NJ, Gelband CH, Georgoulias V, Gerwien RW, Getzenberg RH, Giannini G, Giardiello FM, Gilman AG, Gold B, Goldstein M, Golstein P, Graziani G, Graziosi C, Greten FR, Gu P, Guarente L, Guerrier-Takada C, Gulino A, Gunther EC, Ha JR, Hao Y, Harris CC, Hayashida Y, He X, Hede K, Hedenfalk I, Hengartner H, Hentze MW, Hermonat PL, Herndon E, Heyes MP, Hidalgo M, Hinds PW, Hirohashi S, Hisamuddin IM, Hochberg MC, Hollstein M, Honda K, Howitz KT, Hsu D, Huang S, Hwang 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