_______________The Other 90% of Science_______________

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Darnton SJ et al

ViewRank: 501
Int J Cancer 2005 Jun 20;115(3):351-8      
Tissue inhibitor of metalloproteinase-3 (TIMP-3) gene is methylated in the development of esophageal adenocarcinoma: loss of expression correlates with poor prognosis.


Counter CM et al

ViewRank: 502
EMBO J 1992 May;11(5):1921-9      
Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity.


Hwang WS et al

ViewRank: 503
Science 2005 Jun 17;308(5729):1777-83      
Patient-specific embryonic stem cells derived from human SCNT blastocysts.


Kang Y et al

ViewRank: 504
Proc Natl Acad Sci U S A 2005 Sep 27;102(39):13909-14      
Breast cancer bone metastasis mediated by the Smad tumor suppressor pathway.


Pagès F et al

ViewRank: 505
N Engl J Med 2005 Dec 22;353(25):2654-66      
Effector memory T cells, early metastasis, and survival in colorectal cancer.


Arnold K et al

ViewRank: 506
Cancer Lett 2006 Nov 8;243(1):90-100      
Lower level of BRCA2 protein in heterozygous mutation carriers is correlated with an increase in DNA double strand breaks and an impaired DSB repair.


Fu X et al

ViewRank: 507
J Biol Chem 2006 Jul 21;281(29):20368-82      
cAMP-response element-binding protein mediates acid-induced NADPH oxidase NOX5-S expression in Barrett esophageal adenocarcinoma cells.


Chisaka O and Capecchi MR

ViewRank: 508
Nature 1991 Apr 11;350(6318):473-9      
Regionally restricted developmental defects resulting from targeted disruption of the mouse homeobox gene hox-1.5.


Won J et al

ViewRank: 509
Nat Chem Biol 2006 Jul;2(7):369-74      
Small molecule-based reversible reprogramming of cellular lifespan.


Abdul Ajees A et al

ViewRank: 510
Nature 2006 Nov 9;444(7116):221-5      
The structure of complement C3b provides insights into complement activation and regulation.


Suetsugu A et al

ViewRank: 511
Biochem Biophys Res Commu 2006 Dec 29;351(4):820-4      
Characterization of CD133+ hepatocellular carcinoma cells as cancer stem/progenitor cells.


Liu R et al

ViewRank: 512
N Engl J Med 2007 Jan 18;356(3):217-26      
The prognostic role of a gene signature from tumorigenic breast-cancer cells.


Jimeno A et al

ViewRank: 513
Mol Cancer Ther 2007 Mar;6(3):1079-88      
Dual mitogen-activated protein kinase and epidermal growth factor receptor inhibition in biliary and pancreatic cancer.


Souglakos J et al

ViewRank: 514
Dig Dis 2007;25(1):100-5      
Irinotecan plus weekly 5-fluorouracil and leucovorin as salvage treatment for patients with metastatic colorectal cancer: a phase II trial.


Yeager M et al

ViewRank: 515
Nat Genet 2007 May;39(5):645-9      
Genome-wide association study of prostate cancer identifies a second risk locus at 8q24.


Stupp R and Hegi ME

ViewRank: 516
J Clin Oncol 2007 Apr 20;25(12):1459-60      
Methylguanine methyltransferase testing in glioblastoma: when and how?


Chendrimada TP et al

ViewRank: 517
Nature 2007 Jun 14;447(7146):823-8      
MicroRNA silencing through RISC recruitment of eIF6.


Ray PS and Fox PL

ViewRank: 518
EMBO J 2007 Jul 25;26(14):3360-72      
A post-transcriptional pathway represses monocyte VEGF-A expression and angiogenic activity.


Pfeiffer T and Hoffmann R

ViewRank: 519
Proc Natl Acad Sci U S A 2007 Jul 17;104(29):12052-6      
Temporal patterns of genes in scientific publications.


Henschke CI

ViewRank: 520
Clin Cancer Res 2007 Sep 1;13(17):4949-50      
Survival of patients with clinical stage I lung cancer diagnosed by computed tomography screening for lung cancer.


Nakahara T et al

ViewRank: 521
Cancer Res 2007 Sep 1;67(17):8014-21      
YM155, a novel small-molecule survivin suppressant, induces regression of established human hormone-refractory prostate tumor xenografts.


Srivastava JK and Gupta S

ViewRank: 522
J Agric Food Chem 2007 Nov 14;55(23):9470-8      
Antiproliferative and apoptotic effects of chamomile extract in various human cancer cells.


Milne JC et al

ViewRank: 523
Nature 2007 Nov 29;450(7170):712-6      
Small molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetes.


Tavazoie SF et al

ViewRank: 524
Nature 2008 Jan 10;451(7175):147-52      
Endogenous human microRNAs that suppress breast cancer metastasis.


Lutsey PL et al

ViewRank: 525
Circulation 2008 Feb 12;117(6):754-61      
Dietary intake and the development of the metabolic syndrome: the Atherosclerosis Risk in Communities study.


Tsai J et al

ViewRank: 526
Proc Natl Acad Sci U S A 2008 Feb 26;105(8):3041-6      
Discovery of a selective inhibitor of oncogenic B-Raf kinase with potent antimelanoma activity.


Lee SK et al

ViewRank: 527
J Cell Physiol 2008 Jul;216(1):180-8      
Vitamin C suppresses proliferation of the human melanoma cell SK-MEL-2 through the inhibition of cyclooxygenase-2 (COX-2) expression and the modulation of insulin-like growth factor II (IGF-II) production.


Ogunwobi OO and Beales IL

ViewRank: 528
Mol Cell Endocrinol 2008 Mar 26;285(1-2):43-50      
Globular adiponectin, acting via adiponectin receptor-1, inhibits leptin-stimulated oesophageal adenocarcinoma cell proliferation.


Ma PC et al

ViewRank: 529
Genes Chromosomes Cancer 2008 Dec;47(12):1025-37      
Expression and mutational analysis of MET in human solid cancers.


van Rooij E et al

ViewRank: 530
Proc Natl Acad Sci U S A 2008 Sep 2;105(35):13027-32      
Dysregulation of microRNAs after myocardial infarction reveals a role of miR-29 in cardiac fibrosis.


Keswani RN et al

ViewRank: 531
Dis Esophagus 2008;21(6):514-21      
Sorafenib inhibits MAPK-mediated proliferation in a Barrett's esophageal adenocarcinoma cell line.


Garman KS et al

ViewRank: 532
Proc Natl Acad Sci U S A 2008 Dec 9;105(49):19432-7      
A genomic approach to colon cancer risk stratification yields biologic insights into therapeutic opportunities.


Zhao S et al

ViewRank: 533
Science 2009 Apr 10;324(5924):261-5      
Glioma-derived mutations in IDH1 dominantly inhibit IDH1 catalytic activity and induce HIF-1alpha.


Bos PD et al

ViewRank: 534
Nature 2009 Jun 18;459(7249):1005-9      
Genes that mediate breast cancer metastasis to the brain.


Rhodes DR et al

ViewRank: 535
Proc Natl Acad Sci U S A 2009 Jun 23;106(25):10284-9      
AGTR1 overexpression defines a subset of breast cancer and confers sensitivity to losartan, an AGTR1 antagonist.


Messersmith WA et al

ViewRank: 536
Mol Cancer Ther 2009 Jun;8(6):1484-93      
Efficacy and pharmacodynamic effects of bosutinib (SKI-606), a Src/Abl inhibitor, in freshly generated human pancreas cancer xenografts.


Amundadottir L et al

ViewRank: 537
Nat Genet 2009 Sep;41(9):986-90      
Genome-wide association study identifies variants in the ABO locus associated with susceptibility to pancreatic cancer.


Collins R et al

ViewRank: 538
Lancet 1990 Apr 7;335(8693):827-38      
Blood pressure, stroke, and coronary heart disease. Part 2, Short-term reductions in blood pressure: overview of randomised drug trials in their epidemiological context.


Beloqui A et al

ViewRank: 539
Science 2009 Oct 9;326(5950):252-7      
Reactome array: forging a link between metabolome and genome.


Diede SJ et al

ViewRank: 540
Proc Natl Acad Sci U S A 2010 Jan 5;107(1):234-9      
DNA methylation of developmental genes in pediatric medulloblastomas identified by denaturation analysis of methylation differences.


Jentzmik F et al

ViewRank: 541
Eur Urol 2010 Jul;58(1):12-8; discussio      
Sarcosine in urine after digital rectal examination fails as a marker in prostate cancer detection and identification of aggressive tumours.


Heidorn SJ et al

ViewRank: 542
Cell 2010 Jan 22;140(2):209-21      
Kinase-dead BRAF and oncogenic RAS cooperate to drive tumor progression through CRAF.


Kasowski M et al

ViewRank: 543
Science 2010 Apr 9;328(5975):232-5      
Variation in transcription factor binding among humans.


Lee JH et al

ViewRank: 544
Proc Natl Acad Sci U S A 2010 Aug 17;107(33):14639-44      
Histone deacetylase inhibitor induces DNA damage, which normal but not transformed cells can repair.


Culler SJ et al

ViewRank: 545
Science 2010 Nov 26;330(6008):1251-5      
Reprogramming cellular behavior with RNA controllers responsive to endogenous proteins.


Antonyak MA et al

ViewRank: 546
Proc Natl Acad Sci U S A 2011 Mar 22;108(12):4852-7      
Cancer cell-derived microvesicles induce transformation by transferring tissue transglutaminase and fibronectin to recipient cells.


Huryn DM et al

ViewRank: 547
Proc Natl Acad Sci U S A 2011 Apr 26;108(17):6757-62      
Chemical methodology as a source of small-molecule checkpoint inhibitors and heat shock protein 70 (Hsp70) modulators.


Wigler M et al

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Cell 1979 Apr;16(4):777-85      
Transformation of mammalian cells with genes from procaryotes and eucaryotes.


Altschul SF et al

ViewRank: 549
J Mol Biol 1990 Oct 5;215(3):403-10      
Basic local alignment search tool.


Saiki RK et al

ViewRank: 550
Science 1988 Jan 29;239(4839):487-91      
Primer-directed enzymatic amplification of DNA with a thermostable DNA polymerase.


Nakamura T et al

ViewRank: 551
Nature 1989 Nov 23;342(6248):440-3      
Molecular cloning and expression of human hepatocyte growth factor.


Lippincott-Schwartz J et al

ViewRank: 552
Cell 1989 Mar 10;56(5):801-13      
Rapid redistribution of Golgi proteins into the ER in cells treated with brefeldin A: evidence for membrane cycling from Golgi to ER.


Ignarro LJ et al

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Proc Natl Acad Sci U S A 1987 Dec;84(24):9265-9      
Endothelium-derived relaxing factor produced and released from artery and vein is nitric oxide.


Finlay CA et al

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Mol Cell Biol 1988 Feb;8(2):531-9      
Activating mutations for transformation by p53 produce a gene product that forms an hsc70-p53 complex with an altered half-life.


Schwarz RE et al

ViewRank: 555
J Immunol 1988 Nov 15;141(10):3318-23      
The expression and functional involvement of laminin-like molecules in non-MHC restricted cytotoxicity by human Leu-19+/CD3- natural killer lymphocytes.


Gould SJ

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Science 1978 May 5;200(4341):503-9      
Morton's ranking of races by cranial capacity. Unconscious manipulation of data may be a scientific norm.


Doetschman T et al

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Nature 1987 Dec 10-16;330(6148):576-8      
Targetted correction of a mutant HPRT gene in mouse embryonic stem cells.


Glucksberg H et al

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Transplantation 1974 Oct;18(4):295-304      
Clinical manifestations of graft-versus-host disease in human recipients of marrow from HL-A-matched sibling donors.


Tsien RY

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Biochemistry 1980 May 27;19(11):2396-404      
New calcium indicators and buffers with high selectivity against magnesium and protons: design, synthesis, and properties of prototype structures.


Schwab M et al

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Nature 1983 Sep 15-21;305(5931):245-8      
Amplified DNA with limited homology to myc cellular oncogene is shared by human neuroblastoma cell lines and a neuroblastoma tumour.


Kägi D et al

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Science 1994 Jul 22;265(5171):528-30      
Fas and perforin pathways as major mechanisms of T cell-mediated cytotoxicity.


Resnicoff M et al

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Cancer Res 1995 Sep 1;55(17):3739-41      
Correlation between apoptosis, tumorigenesis, and levels of insulin-like growth factor I receptors.


Yang E et al

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Cell 1995 Jan 27;80(2):285-91      
Bad, a heterodimeric partner for Bcl-XL and Bcl-2, displaces Bax and promotes cell death.


Ford D et al

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Lancet 1994 Mar 19;343(8899):692-5      
Risks of cancer in BRCA1-mutation carriers. Breast Cancer Linkage Consortium.


el-Deiry WS et al

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Cancer Res 1994 Mar 1;54(5):1169-74      
WAF1/CIP1 is induced in p53-mediated G1 arrest and apoptosis.


Peters WP et al

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J Clin Oncol 1993 Jun;11(6):1132-43      
High-dose chemotherapy and autologous bone marrow support as consolidation after standard-dose adjuvant therapy for high-risk primary breast cancer.


Bochelen D et al

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J Pharmacol Exp Ther 1999 Feb;288(2):653-9      
Calcineurin inhibitors FK506 and SDZ ASM 981 alleviate the outcome of focal cerebral ischemic/reperfusion injury.


Klivenyi P et al

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Nat Med 1999 Mar;5(3):347-50      
Neuroprotective effects of creatine in a transgenic animal model of amyotrophic lateral sclerosis.


Kleeff J et al

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Gastroenterology 1999 May;116(5):1202-16      
Bone morphogenetic protein 2 exerts diverse effects on cell growth in vitro and is expressed in human pancreatic cancer in vivo.


Venter JC et al

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Science 2001 Feb 16;291(5507):1304-51      
The sequence of the human genome.


Tissenbaum HA and Guarente L

ViewRank: 571
Nature 2001 Mar 8;410(6825):227-30      
Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans.


Kumar MS et al

ViewRank: 572
Biochemistry 2002 Oct 1;41(39):11681-91      
Structures of apolipoprotein A-II and a lipid-surrogate complex provide insights into apolipoprotein-lipid interactions.


Furchgott RF and Bhadrakom S

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J Pharmacol Exp Ther 1953 Jun;108(2):129-43      
Reactions of strips of rabbit aorta to epinephrine, isopropylarterenol, sodium nitrite and other drugs.


Sabah M et al

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Hum Pathol 2004 Oct;35(10):1231-5      
Expression of human telomerase reverse transcriptase in gastrointestinal stromal tumors occurs preferentially in malignant neoplasms.


Birkenkamp-Demtroder K et al

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Gut 2005 Mar;54(3):374-84      
Differential gene expression in colon cancer of the caecum versus the sigmoid and rectosigmoid.


Ekstrand AJ et al

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Proc Natl Acad Sci U S A 1992 May 15;89(10):4309-13      
Amplified and rearranged epidermal growth factor receptor genes in human glioblastomas reveal deletions of sequences encoding portions of the N- and/or C-terminal tails.


Zachara BA et al

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Neoplasma 2005;52(3):248-54      
Blood and tissue selenium concentrations and glutathione peroxidase activities in patients with prostate cancer and benign prostate hyperplasia.


Choi SJ et al

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Mol Cell Biochem 2005 Mar;271(1-2):23-8      
Tsc-22 enhances TGF-beta signaling by associating with Smad4 and induces erythroid cell differentiation.


Glinsky GV et al

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J Clin Invest 2005 Jun;115(6):1503-21      
Microarray analysis identifies a death-from-cancer signature predicting therapy failure in patients with multiple types of cancer.


Michl J et al

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Int J Cancer 2006 Oct 1;119(7):1577-85      
PNC-28, a p53-derived peptide that is cytotoxic to cancer cells, blocks pancreatic cancer cell growth in vivo.


Malik M et al

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Mol Cancer Ther 2006 Jun;5(6):1405-14      
Roles of nonhomologous end-joining pathways in surviving topoisomerase II-mediated DNA damage.


Matsuyama W et al

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Blood 2007 Jan 1;109(1):22-30      
Discoidin domain receptor 1 contributes to eosinophil survival in an NF-kappaB-dependent manner in Churg-Strauss syndrome.


Si J et al

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J Biol Chem 2007 Jun 1;282(22):16244-55      
NADPH oxidase NOX5-S mediates acid-induced cyclooxygenase-2 expression via activation of NF-kappaB in Barrett's esophageal adenocarcinoma cells.


Levy L et al

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Mol Cell Biol 2007 Sep;27(17):6068-83      
Arkadia activates Smad3/Smad4-dependent transcription by triggering signal-induced SnoN degradation.


Hao Y et al

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BMC Gastroenterol 2007 Jun 27;7:24      
Gene expression changes associated with Barrett's esophagus and Barrett's-associated adenocarcinoma cell lines after acid or bile salt exposure.


Ahmed FE et al

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Cancer Genomics Proteomic 2007 Jan-Feb;4(1):1-20      
Transcriptomic molecular markers for screening human colon cancer in stool and tissue.


Evers B et al

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Clin Cancer Res 2008 Jun 15;14(12):3916-25      
Selective inhibition of BRCA2-deficient mammary tumor cell growth by AZD2281 and cisplatin.


Melo SA et al

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Nat Genet 2009 Mar;41(3):365-70      
A TARBP2 mutation in human cancer impairs microRNA processing and DICER1 function.


Kopetz S et al

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Cancer Res 2009 May 1;69(9):3842-9      
Synergistic activity of the SRC family kinase inhibitor dasatinib and oxaliplatin in colon carcinoma cells is mediated by oxidative stress.


Blecharz-Klin K et al

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Acta Neurobiol Exp (Wars) 2009;69(2):217-31      
Pharmacological and biochemical effects of Ginkgo biloba extract on learning, memory consolidation and motor activity in old rats.


Dhruva SS et al

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JAMA 2009 Dec 23;302(24):2679-85      
Strength of study evidence examined by the FDA in premarket approval of cardiovascular devices.


Zhang G et al

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Proc Natl Acad Sci U S A 2010 Jan 12;107(2):732-7      
Suppression of human prostate tumor growth by a unique prostate-specific monoclonal antibody F77 targeting a glycolipid marker.


Hatzivassiliou G et al

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Nature 2010 Mar 18;464(7287):431-5      
RAF inhibitors prime wild-type RAF to activate the MAPK pathway and enhance growth.


Schaeffer HJ et al

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Nature 1978 Apr 13;272(5654):583-5      
9-(2-hydroxyethoxymethyl) guanine activity against viruses of the herpes group.


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Transcriptional regulation of BRCA1 expression by a metabolic switch.


DeCaprio JA et al

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SV40 large tumor antigen forms a specific complex with the product of the retinoblastoma susceptibility gene.


Poehlman ET et al

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Changes in energy balance and body composition at menopause: a controlled longitudinal study.


Johnson TR et al

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Gene therapy of rat brain glioblastoma by an episome-based transcriptional cassette expressing antisense IGF-I cDNA.


Higashikawa K et al

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Evaluation of CD44 transcription variants in human digestive tract carcinomas and normal tissues.


Kanowski S et al

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Proof of efficacy of the ginkgo biloba special extract EGb 761 in outpatients suffering from mild to moderate primary degenerative dementia of the Alzheimer type or multi-infarct dementia.

Authors represented in these publications:

Aaltonen LA, Abdul Ajees A, Abraham D, Acharya CR, Adams MD, Agelaki S, Ahmed FE, Ahn JH, Ahn YW, Alarcón C, Alitalo K, Altschul SF, Amador ML, Amundadottir L, Androulakis N, Anthony DD, Antonyak MA, Aoki H, Arimura K, Arnold K, Artis DR, Ateeq B, Avilion AA, Axel R, BHADRAKOM S, Bacchetti S, Baserga R, Bast RC Jr, Bauer DJ, Beal MF, Beales IL, Beauchamp L, Beer DG, Behar J, Beloqui A, Belvin M, Berezovska O, Berger A, Bero LA, Birkenkamp-Demtroder K, Bishop DT, Bissonnette M, Blasberg R, Blecharz-Klin K, Bloch-Boguslawska E, Bochelen D, Boise LH, Bollag G, Bonifacino JS, Boroughs LK, Bos PD, Brandt-Rauf P, Brodeur G, Brodsky JL, Brummond KM, Bryant KL, Buga GM, Burgaud JL, Burrell M, Byrns RE, Büchler MW, Camus M, Cao Q, Cao W, Capecchi MR, Carson M, Casson AG, Cerione RA, Chandra J, Chang KY, Chanock SJ, Chaudhuri G, Chen GY, Chendrimada TP, Chinnaiyan AM, Chisaka O, Choi SJ, Choy ML, Chumsangsri A, Clarke MF, Clift RA, Cohen EE, Collins P, Collins R, Collins VP, Counter CM, Culler SJ, Cummins R, Dallas NA, Darnton SJ, Das D, De Siervi A, DeCaprio JA, Delgado J, Dhruva SS, Di LJ, Diede SJ, Doetschman T, Drost R, Easton DF, Edelman E, Ekstrand AJ, Elion GB, Eliyahu D, Elliott PJ, Ellis LM, Enriquez-Rios V, Episkopou V, Erlich HA, Esteller M, Evers B, FURCHGOTT RF, Fefer A, Fernandez AG, Ferrante RJ, Ferrer M, Figge J, Fine RL, Finlay CA, Finn KJ, Foekens JA, Ford D, Foster SS, Fox PL, Frerk K, Fridman WH, Friedman LS, Friess H, Fu X, Gallick GE, Galon J, Gardner AW, Gardner K, Garman KS, Gelfand DH, Geng LN, Georgoulias V, Gerald WL, Gerstein MB, Gish W, Glinskii AB, Glinsky GV, Glucksberg H, Goldgar DE, Goldstein M, Golstein P, Golyshin PN, Gould SJ, Greene MI, Gregg RG, Greider CW, Grubert F, Guan KL, Guarente L, Guazzaroni ME, Guenthoer J, Gunasekaran K, Gupta S, Hagiya M, Han TH, Hao Y, Hardie LJ, Harkin S, Harley CB, Harper JW, Hartge P, Hatzivassiliou G, Hayes RB, He W, Heffelfinger C, Hegi ME, Heidorn SJ, Hengartner H, Hennekens CH, Henschke CI, Herlyn 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