_______________The Other 90% of Science_______________

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Ong CW et al

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Mod Pathol 2010 Mar;23(3):450-7      
CD133 expression predicts for non-response to chemotherapy in colorectal cancer.


Jentzmik F et al

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Eur Urol 2010 Jul;58(1):12-8; discussio      
Sarcosine in urine after digital rectal examination fails as a marker in prostate cancer detection and identification of aggressive tumours.


Halaban R et al

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Pigment Cell Melanoma Res 2010 Apr;23(2):190-200      
PLX4032, a selective BRAF(V600E) kinase inhibitor, activates the ERK pathway and enhances cell migration and proliferation of BRAF melanoma cells.


Spadoni A and Daraio C

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Proc Natl Acad Sci U S A 2010 Apr 20;107(16):7230-4      
Generation and control of sound bullets with a nonlinear acoustic lens.


Schaeffer HJ et al

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Nature 1978 Apr 13;272(5654):583-5      
9-(2-hydroxyethoxymethyl) guanine activity against viruses of the herpes group.


Forman D et al

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BMJ 1991 Jun 1;302(6788):1302-5      
Association between infection with Helicobacter pylori and risk of gastric cancer: evidence from a prospective investigation.


Lee JH et al

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Proc Natl Acad Sci U S A 2010 Aug 17;107(33):14639-44      
Histone deacetylase inhibitor induces DNA damage, which normal but not transformed cells can repair.


Vignoli M et al

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Pharmacol Res 2011 Sep;64(3):242-8      
Thymidylate synthase expression and genotype have no major impact on the clinical outcome of colorectal cancer patients treated with 5-fluorouracil.


Nakamura T et al

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Nature 1989 Nov 23;342(6248):440-3      
Molecular cloning and expression of human hepatocyte growth factor.


Ignarro LJ et al

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Proc Natl Acad Sci U S A 1987 Dec;84(24):9265-9      
Endothelium-derived relaxing factor produced and released from artery and vein is nitric oxide.


Finlay CA et al

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Mol Cell Biol 1988 Feb;8(2):531-9      
Activating mutations for transformation by p53 produce a gene product that forms an hsc70-p53 complex with an altered half-life.


Whyte P et al

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Nature 1988 Jul 14;334(6178):124-9      
Association between an oncogene and an anti-oncogene: the adenovirus E1A proteins bind to the retinoblastoma gene product.


Thoma F et al

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J Cell Biol 1979 Nov;83(2 Pt 1):403-27      
Involvement of histone H1 in the organization of the nucleosome and of the salt-dependent superstructures of chromatin.


Popovic M et al

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Science 1984 May 4;224(4648):497-500      
Detection, isolation, and continuous production of cytopathic retroviruses (HTLV-III) from patients with AIDS and pre-AIDS.


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Biochemistry 1980 May 27;19(11):2396-404      
New calcium indicators and buffers with high selectivity against magnesium and protons: design, synthesis, and properties of prototype structures.


Kharitonov SA et al

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Increased nitric oxide in exhaled air of asthmatic patients.


Bochelen D et al

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J Pharmacol Exp Ther 1999 Feb;288(2):653-9      
Calcineurin inhibitors FK506 and SDZ ASM 981 alleviate the outcome of focal cerebral ischemic/reperfusion injury.


Soldes OS et al

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Br J Cancer 1999 Feb;79(3-4):595-603      
Differential expression of Hsp27 in normal oesophagus, Barrett's metaplasia and oesophageal adenocarcinomas.


Klivenyi P et al

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Nat Med 1999 Mar;5(3):347-50      
Neuroprotective effects of creatine in a transgenic animal model of amyotrophic lateral sclerosis.


Tetsu O and McCormick F

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Nature 1999 Apr 1;398(6726):422-6      
Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells.


Kleeff J et al

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Gastroenterology 1999 May;116(5):1202-16      
Bone morphogenetic protein 2 exerts diverse effects on cell growth in vitro and is expressed in human pancreatic cancer in vivo.


Contreras JL et al

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Transplantation 1999 Jul 27;68(2):215-9      
Tolerability and side effects of anti-CD3-immunotoxin in preclinical testing in kidney and pancreatic islet transplant recipients.


Etheredge JA et al

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Proc Natl Acad Sci U S A 1999 Nov 23;96(24):13845-6      
Monarch butterflies (Danaus plexippus L.) use a magnetic compass for navigation.


Broeks A et al

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Am J Hum Genet 2000 Feb;66(2):494-500      
ATM-heterozygous germline mutations contribute to breast cancer-susceptibility.


Neher E and Sakmann B

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Single-channel currents recorded from membrane of denervated frog muscle fibres.


Venter JC et al

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Science 2001 Feb 16;291(5507):1304-51      
The sequence of the human genome.


Hedenfalk I et al

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N Engl J Med 2001 Feb 22;344(8):539-48      
Gene-expression profiles in hereditary breast cancer.


Pedersen MW et al

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Ann Oncol 2001 Jun;12(6):745-60      
The type III epidermal growth factor receptor mutation. Biological significance and potential target for anti-cancer therapy.


Liu H et al

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J Mol Cell Cardiol 2001 Nov;33(11):2007-14      
Role of opioid delta1 receptors, mitochondrial K(ATP) channels, and protein kinase C during cardiocyte apoptosis.


Tascilar M et al

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Clin Cancer Res 2001 Dec;7(12):4115-21      
The SMAD4 protein and prognosis of pancreatic ductal adenocarcinoma.


Giannini G et al

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EMBO Rep 2002 Mar;3(3):248-54      
Human MRE11 is inactivated in mismatch repair-deficient cancers.


Kim JH et al

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JAMA 2002 Apr 3;287(13):1671-9      
Osteopontin as a potential diagnostic biomarker for ovarian cancer.


Goode EL et al

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Cancer Res 2002 Jun 1;62(11):3052-7      
Effect of germ-line genetic variation on breast cancer survival in a population-based study.


Maitland-van der Zee AH et al

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Atherosclerosis 2002 Aug;163(2):213-22      
Genetic polymorphisms: importance for response to HMG-CoA reductase inhibitors.


Mootha VK et al

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Nat Genet 2003 Jul;34(3):267-73      
PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes.



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J Biol Chem 1962 May;237:1555-62      
Isolation of a mouse submaxillary gland protein accelerating incisor eruption and eyelid opening in the new-born animal.


Furuichi Y et al

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J Cereb Blood Flow Metab 2003 Oct;23(10):1183-94      
Tacrolimus, a potential neuroprotective agent, ameliorates ischemic brain damage and neurologic deficits after focal cerebral ischemia in nonhuman primates.


Su YH et al

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J Mol Diagn 2004 May;6(2):101-7      
Human urine contains small, 150 to 250 nucleotide-sized, soluble DNA derived from the circulation and may be useful in the detection of colorectal cancer.


Osafune T et al

ViewRank: 539
Anal Sci 2004 Jun;20(6):971-4      
Influence of the pH on separating DNA by high-speed microchip electrophoresis.


Tse AN and Schwartz GK

ViewRank: 540
Cancer Res 2004 Sep 15;64(18):6635-44      
Potentiation of cytotoxicity of topoisomerase i poison by concurrent and sequential treatment with the checkpoint inhibitor UCN-01 involves disparate mechanisms resulting in either p53-independent clonogenic suppression or p53-dependent mitotic catas


Mombaerts P et al

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RAG-1-deficient mice have no mature B and T lymphocytes.


Zachara BA et al

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Neoplasma 2005;52(3):248-54      
Blood and tissue selenium concentrations and glutathione peroxidase activities in patients with prostate cancer and benign prostate hyperplasia.


Hwang WS et al

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Science 2005 Jun 17;308(5729):1777-83      
Patient-specific embryonic stem cells derived from human SCNT blastocysts.


Hardy PA and Zacharias H

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Cell Biol Int 2005 Dec;29(12):983-92      
Reappraisal of the Hansemann-Boveri hypothesis on the origin of tumors.


Pagès F et al

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N Engl J Med 2005 Dec 22;353(25):2654-66      
Effector memory T cells, early metastasis, and survival in colorectal cancer.


Fu X et al

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J Biol Chem 2006 Jul 21;281(29):20368-82      
cAMP-response element-binding protein mediates acid-induced NADPH oxidase NOX5-S expression in Barrett esophageal adenocarcinoma cells.


Won J et al

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Nat Chem Biol 2006 Jul;2(7):369-74      
Small molecule-based reversible reprogramming of cellular lifespan.


Rubio-Viqueira B et al

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Clin Cancer Res 2006 Aug 1;12(15):4652-61      
An in vivo platform for translational drug development in pancreatic cancer.


Brinkman M et al

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Eur J Cancer 2006 Oct;42(15):2463-71      
Are men with low selenium levels at increased risk of prostate cancer?


Mozaffarian D and Rimm EB

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JAMA 2006 Oct 18;296(15):1885-99      
Fish intake, contaminants, and human health: evaluating the risks and the benefits.


Dewan A et al

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Science 2006 Nov 10;314(5801):989-92      
HTRA1 promoter polymorphism in wet age-related macular degeneration.


Kapasi P et al

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Mol Cell 2007 Jan 12;25(1):113-26      
L13a blocks 48S assembly: role of a general initiation factor in mRNA-specific translational control.


Liu R et al

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N Engl J Med 2007 Jan 18;356(3):217-26      
The prognostic role of a gene signature from tumorigenic breast-cancer cells.


Levy L et al

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Arkadia activates Smad3/Smad4-dependent transcription by triggering signal-induced SnoN degradation.


Jerne NK and Nordin AA

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Plaque Formation in Agar by Single Antibody-Producing Cells.


Wijnhoven TJ et al

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J Am Soc Nephrol 2007 Dec;18(12):3119-27      
Removal of heparan sulfate from the glomerular basement membrane blocks protein passage.


Milne JC et al

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Nature 2007 Nov 29;450(7170):712-6      
Small molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetes.


Montesano R et al

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Identification of a fibroblast-derived epithelial morphogen as hepatocyte growth factor.


Dhruva SS et al

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Strength of study evidence examined by the FDA in premarket approval of cardiovascular devices.


Huryn DM et al

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Proc Natl Acad Sci U S A 2011 Apr 26;108(17):6757-62      
Chemical methodology as a source of small-molecule checkpoint inhibitors and heat shock protein 70 (Hsp70) modulators.


Wright NA et al

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Induction of a novel epidermal growth factor-secreting cell lineage by mucosal ulceration in human gastrointestinal stem cells.


Mansour SL et al

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Disruption of the proto-oncogene int-2 in mouse embryo-derived stem cells: a general strategy for targeting mutations to non-selectable genes.


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Methotrexate and cyclosporine compared with cyclosporine alone for prophylaxis of acute graft versus host disease after marrow transplantation for leukemia.


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Human papillomavirus types 6 and 11 DNA sequences in genital and laryngeal papillomas and in some cervical cancers.


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Schwab M et al

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Nature 1983 Sep 15-21;305(5931):245-8      
Amplified DNA with limited homology to myc cellular oncogene is shared by human neuroblastoma cell lines and a neuroblastoma tumour.


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Changes in energy balance and body composition at menopause: a controlled longitudinal study.


Games D et al

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Nature 1995 Feb 9;373(6514):523-7      
Alzheimer-type neuropathology in transgenic mice overexpressing V717F beta-amyloid precursor protein.


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WAF1/CIP1 is induced in p53-mediated G1 arrest and apoptosis.


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An international randomized trial comparing four thrombolytic strategies for acute myocardial infarction. The GUSTO investigators.


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ONYX-015, an E1B gene-attenuated adenovirus, causes tumor-specific cytolysis and antitumoral efficacy that can be augmented by standard chemotherapeutic agents.


Brodie SJ et al

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Am J Pathol 1999 May;154(5):1453-64      
Pediatric AIDS-associated lymphocytic interstitial pneumonia and pulmonary arterio-occlusive disease: role of VCAM-1/VLA-4 adhesion pathway and human herpesviruses.


Ozaki S et al

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Blood 1999 Jun 1;93(11):3922-30      
Humanized anti-HM1.24 antibody mediates myeloma cell cytotoxicity that is enhanced by cytokine stimulation of effector cells.


Bombardier C et al

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N Engl J Med 2000 Nov 23;343(21):1520-8, 2       
Comparison of upper gastrointestinal toxicity of rofecoxib and naproxen in patients with rheumatoid arthritis. VIGOR Study Group.


Tissenbaum HA and Guarente L

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Nature 2001 Mar 8;410(6825):227-30      
Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans.


Andreassen PR et al

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Mol Biol Cell 2001 May;12(5):1315-28      
Tetraploid state induces p53-dependent arrest of nontransformed mammalian cells in G1.


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J Natl Cancer Inst 2001 Jul 18;93(14):1054-61      
Phases of biomarker development for early detection of cancer.


Sartippour MR et al

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Oncol Rep 2001 Nov-Dec;8(6):1355-7      
Livistona extract inhibits angiogenesis and cancer growth.


Kumar MS et al

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Biochemistry 2002 Oct 1;41(39):11681-91      
Structures of apolipoprotein A-II and a lipid-surrogate complex provide insights into apolipoprotein-lipid interactions.


Barratt PL et al

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Lancet 2002 Nov 2;360(9343):1381-91      
DNA markers predicting benefit from adjuvant fluorouracil in patients with colon cancer: a molecular study.


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Cancer Cell 2003 Aug;4(2):111-20      
Tumor induction by an endogenous K-ras oncogene is highly dependent on cellular context.


Darnton SJ et al

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Tissue inhibitor of metalloproteinase-3 (TIMP-3) gene is methylated in the development of esophageal adenocarcinoma: loss of expression correlates with poor prognosis.


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Atherosclerosis 2005 Jun;180(2):407-15      
A promoter polymorphism in cholesterol 7alpha-hydroxylase interacts with apolipoprotein E genotype in the LDL-lowering response to atorvastatin.


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Microarray analysis identifies a death-from-cancer signature predicting therapy failure in patients with multiple types of cancer.


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Regionally restricted developmental defects resulting from targeted disruption of the mouse homeobox gene hox-1.5.


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Gene expression changes associated with Barrett's esophagus and Barrett's-associated adenocarcinoma cell lines after acid or bile salt exposure.


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Lower level of BRCA2 protein in heterozygous mutation carriers is correlated with an increase in DNA double strand breaks and an impaired DSB repair.

Authors represented in these publications:

Adams D, Adams MD, Alessandrini R, Alexopoulou L, Alitalo K, Altshuler D, Andreassen PR, Anthony DD, Arango D, Arii K, Arii T, Arnold K, Augenlicht LH, Baba Y, Bacchiocchi A, Barbacid M, Barnes PJ, Barnstable C, Barratt PL, Bauer DJ, Beal MF, Beauchamp L, Beer DG, Behar J, Berden JH, Berezovska O, Berger A, Berkowitz RS, Bero LA, Bignold LP, Birbeck K, Bittner M, Blobel G, Bloch-Boguslawska E, Block TM, Bochelen D, Bombardier C, Brenner DE, Brinkman M, Brodeur G, Brodie SJ, Brodsky JL, Broeks A, Brousseau ME, Brummond KM, Buchkovich KJ, Buga GM, Buntinx F, Burrell M, Byrns RE, Büchler MW, COHEN S, Califf R, Campuzano V, Camus M, Cao W, Capecchi MR, Carson M, Cartner S, Casson AG, Catalano PJ, Cerignoli F, Chamaret S, Champagne E, Chang KY, Chaudhuri G, Chaudhuri S, Chen GY, Chisaka O, Choy ML, Clarke MF, Cochran BH, Coghlan BL, Collins P, Contreras JL, Corner GA, Covell DG, Cramer DW, Crouch J, Cusatis G, Damstrup L, Daraio C, Darnton SJ, Das D, DeWitt D, Deeg HJ, Dewan A, Dhawahir A, Dhruva SS, Diem K, Dobberstein B, Dunning AM, Easton DF, Eckhoff DE, Elia G, Elion GB, Eliyahu D, Elliott PJ, Enriquez-Rios V, Episkopou V, Eriksson KF, Etheredge JA, Etzioni R, Feng Z, Ferrante RJ, Finlay CA, Flavell RA, Fletcher JE, Floore AN, Forman D, Foster SS, Fox PL, Frati L, Frerk K, Fridman WH, Friess H, Fu X, Fujimori K, Fullerton F, Furuichi Y, Gallo RC, Galon J, Games D, Gardner AW, Genuardi M, Giannini G, Gissmann L, Glinskii AB, Glinsky GV, Gluckman JC, Go VL, Goggins M, Goldstein M, Goode EL, Goto T, Groop LC, Guarente L, Guerra C, Gulino A, Gupta S, Hagiya M, Halaban R, Hanash SM, Hao Y, Hardie LJ, Hardy PA, Harkin S, Harlow E, Harper JW, Hartman S, Heber D, Hedenfalk I, Heise C, Hennekens CH, Hercend T, Herrup K, Hidalgo M, Hill CS, Hill DE, Hinds PW, Hirschhorn JN, Hochberg MC, Hoh J, Holt AC, Horowitz JM, Howe JG, Howell M, Hruban RH, Huryn DM, Hussain MM, Hwang WS, Iacomini J, Iacopetta B, Iannettoni MD, Ignarro LJ, Ikenberg H, Ilan J, Ishiwata T, Jander 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